Face transplant recipient’s donor face now failing

Face transplant recipient’s donor face now failing

More than 40 patients worldwide have received face transplants

A woman who was severely burned in a domestic violence attack in Vermont is hoping for a second face transplant after doctors recently discovered tissue damage that likely will lead to the loss of her donor face.

Carmen Blandin Tarleton, 51, was burned over 80% of her body when her estranged husband beat her with a baseball bat and doused her body with lye in 2007. Six years ago, she received a face transplant at Brigham and Woman’s Hospital in Boston, where she’s being evaluated for a possible second transplant.

Tarleton, who now lives in Manchester, New Hampshire, told The Boston Globe she has no regrets about the transplant because it dramatically improved her life. She has learned to play the piano and banjo, wrote a memoir and has spoken to many groups about her life. She lost 20 pounds and began walking five miles a week.

“I had such a low quality of life prior to my face transplant. Do I wish it had lasted 10 or 20 years? Of course,” she said.

More than 40 patients worldwide have received face transplants, including 15 in the United States. None of the American patients have lost their donor faces, but last year, a French man whose immune system rejected his donor face eight years after his first transplant underwent a second.

Tarleton’s doctors noted that most transplanted organs have limited life spans. But her situation is a reminder that despite successes in the field, face transplantation is experimental and still a young science with many unanswered questions about benefits versus long-term risks.

“There are so many unknowns and so many new things we are discovering,” said Dr. Bohdan Pomahac, director of plastic surgery transplantation at the Brigham and one of Tarleton’s surgeons. Still, he said, “it’s really not realistic to hope faces are going to last (the patient’s) lifetime.”

READ MORE: US begins organ transplants from living donors who have HIV

Dr. Brian Gastman, a transplant surgeon at the Cleveland Clinic, which did the first U.S. face transplant 11 years ago, said more patients are starting to experience chronic rejection. “We all believe every patient will likely need a retransplant” at some point, he said.

Since her transplant in February 2013, Tarleton has had repeated rejection episodes when her new face became swollen and red. Those episodes were successfully treated, but last month, physicians discovered that some blood vessels to her face had narrowed and closed, causing facial tissue to die. If the damage progresses slowly, she could go on the wait list for another donor face. Under the worst case scenario, the tissue would die quickly, and doctors would have to remove it and reconstruct her original face.

“We all know we are in unchartered waters,” she said. “I would rather not have to go through a catastrophic failure.”

It will take at least a month to evaluate Tarleton and reach a decision about a second transplant, doctors said. Aside from the setback with her face, a synthetic cornea transplanted into her left eye recently failed, leaving her almost blind.

“These are not common things to go wrong, but when things go wrong, you have to deal with it,” she said. “l will get back to where I was. How, I don’t know. I will get through this.”

The Associated Press

READ MORE: Organ donation week particularly personal for Comox Valley nurse

Like us on Facebook and follow us on Twitter

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

A woman wears a protective face covering to help prevent the spread of COVID-19 as she walks past the emergency entrance of Vancouver General Hospital in Vancouver, B.C., Friday, April 9, 2021. THE CANADIAN PRESS/Jonathan Hayward
54 more cases of COVID-19 in Interior Health

Thirty-two people in the region are in hospital with the virus, 11 of them in intensive care

Williams Lake Pickleball Club members Marykay Simpson and Roy Simpson compete in a friendly game of doubles April 12 at the Kiwanis Tennis Courts in the lakecity. (Greg Sabatino photo - Williams Lake Tribune)
Williams Lake Pickleball Club excited for outdoor season

Club continues to gain popularity in Williams Lake

BC Wildfire Service crew member Josh Hutchinson participated in a controlled burn above the Williams Lake Stampede Grounds on Tuesday, April 20 that was conducted in concert with the Williams Lake Fire Department. It was a good weather day for the burn, as on Wednesday, April 21, the BCWS is urging caution, with strong winds in the forecast Wednesday and Thursday for the region. (Monica Lamb-Yorski photo - Williams Lake Tribune)
Cariboo Fire Centre urges caution against outdoor burning due to strong winds forecast

Public, industry asked to consider postponing burning until calmer weather

Taseko's Gibraltar Mine north of Williams Lake gave 40 layoff-notices Tuesday, April 20. (Photo submitted)
Gibraltar Mine laying off 40 to 60 workers, awaiting permission to reopen existing pit

“It’s unacceptable,” said Williams Lake Mayor Walt Cobb

A syringe is loaded with COVID-19 vaccine at a vaccination clinic run by Vancouver Coastal Health, in Richmond, B.C., Saturday, April 10, 2021. THE CANADIAN PRESS/Jonathan Hayward
67 new cases of COVID-19 in Interior Health

Thirty people in the region are hospitalized with the virus, 11 of whom are intensive care

A large crowd protested against COVID-19 measures at Sunset Beach in Vancouver on Tuesday, April 20, 2021. (Snapchat)
VIDEO: Large, police-patrolled crowds gather at Vancouver beach for COVID protests

Vancouver police said they patrolled the area and monitored all gatherings

Cannabis bought in British Columbia (Ashley Wadhwani/Black Press Media)
Is it time to start thinking about greener ways to package cannabis?

Packaging suppliers are still figuring eco-friendly and affordable packaging options that fit the mandates of Cannabis Regulations

FILE – The Instagram app is shown on an iPhone in Toronto on Monday, March 19, 2018. THE CANADIAN PRESS/Graeme Roy
Judge acquits B.C. teen boy ‘set up’ on sex assault charge based on Instagram messages

The girl and her friends did not have ‘good intentions’ towards the accused, judge says

Kai Palkeinen recently helped a car stuck on the riverbed near the Big Eddy Bridge. While the car could not be saved, some of the driver’s belongings were. It’s common for vehicles to get stuck in the area due to significantly changing river levels from Revelstoke Dam. (Photo by Kai Palkeinen)
“I just sank a car’: Revelstoke resident tries to save vehicle from the Columbia River

Although it’s not permitted, the riverbed near the city is popular for off roading

Meng Wanzhou, chief financial officer of Huawei, walks down the street with an acquaintance after leaving B.C. Supreme Court during a lunch break at her extradition hearing, in Vancouver, B.C., Thursday, April 1, 2021. A judge is scheduled to release her decision today on a request to delay the final leg of hearings in Meng Wanzhou’s extradition case. THE CANADIAN PRESS/Rich Lam
B.C. judge grants Meng Wanzhou’s request to delay extradition hearings

Lawyers for Canada’s attorney general had argued there is no justification to delay proceedings in the case

B.C. Premier John Horgan announces travel restrictions between the province’s regional health authorities at the legislature, April 19, 2021. (B.C. government photo)
B.C. sees 862 more COVID-19 cases Wednesday, seven deaths

Recreational travel restrictions set to begin Friday

B.C. Finance Minister Selina Robinson is photographed following her budget speech in the legislative assembly at the provincial legislature in Victoria, Tuesday, April 20, 2021. THE CANADIAN PRESS/Chad Hipolito
B.C. budget lacks innovative drive, vision during uncertain times, say experts

Finance Minister Selina Robinson’s budget sets out to spend $8.7 billion over three years on infrastructure

Using panels kept cold by water circulating within them, B.C. researchers compared thermal comfort in 60 of the world’s most populous cities, including Toronto. (Lea Ruefenacht)
B.C. researchers use air conditioning to combat spread of COVID particles

Dr. Adam Rysanek and his team have proven a new worthwhile system – a mixture of cooling panels and natural ventilation

Police road checks are coming for people travelling between regions while COVID-19 travel restrictions are in place. (Black Press file photo)
B.C. clarifies COVID-19 travel restrictions, Lower Mainland a single zone

Vehicle checks on highways, at ferry terminals to start Friday

Most Read